moprevention of Pancreatic Cancer: Ready for the Clinic?

نویسندگان

  • D. Logsdon
  • James L. Abbruzzese
چکیده

nloaded ances in our molecular, clinical, and epidemiologic understanding of the risk and development of eatic cancer offer hope for preventing this disease, which is largely intractable once developed. This ctive on provocative, genetically engineered mouse model work reported by Mohammed et al. ning on page 1417 in this issue of the journal) examines the prospects for pancreatic cancer prevention with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). Despite chemo having limited value in advanced pancreatic cancer, EGFR TKIs show promise in the setting of early pancreatic carcinogenesis. Cancer Prev Res; 3(11); 1375–8. ©2010 AACR.

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تاریخ انتشار 2010